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CLPS Antibody (CLPS/9025) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
CLPS/9025
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

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CLPS Antibody (CLPS/9025) [HRP] Summary

Immunogen
Recombinant fragment (around aa1-112) of human CLPS protein (exact sequence is proprietary)
Localization
Secreted.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CLPS
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for CLPS Antibody (CLPS/9025) [HRP]

  • colipase
  • colipase, pancreatic
  • pancreatic colipase preproprotein

Background

The protein encoded by the CLPS gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CLPS