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CD79B Antibody (HM79-11) [PE/Cy5.5]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, IP
Clone
HM79-11
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-65611AF350
Alexa Fluor 405
NB100-65611AF405
Alexa Fluor 488
NB100-65611AF488
Alexa Fluor 532
NB100-65611AF532
Alexa Fluor 594
NB100-65611AF594
Alexa Fluor 647
NB100-65611AF647
Alexa Fluor 700
NB100-65611AF700
Alexa Fluor 750
NB100-65611AF750
Allophycocyanin
NB100-65611APC
Allophycocyanin/Cy7
NB100-65611APCCY7
Biotin
NB100-65611B
CoraFluor 1
NB100-65611CL1
DyLight 350
NB100-65611UV
DyLight 405
NB100-65611V
DyLight 488
NB100-65611G
DyLight 550
NB100-65611R
DyLight 594
NB100-65611DL594
DyLight 650
NB100-65611C
DyLight 680
NB100-65611FR
DyLight 755
NB100-65611IR
FITC
NB100-65611F
FITC
NB100-64017
HRP
NB100-65611H
Janelia Fluor 525
NB100-65611JF525
Janelia Fluor 549
NB100-65611JF549
Janelia Fluor 646
NB100-65611JF646
Janelia Fluor 669
NB100-65611JF669
PE
NB100-65611PE
PE/Atto594
NB100-65611PEATT594
PE/Cy7
NB100-65611PECY7
PerCP
NB100-65611PCP
Unconjugated
NB100-65611
mFluor Violet 450 SE
NB100-65611MFV450
mFluor Violet 500 SE
NB100-65611MFV500
mFluor Violet 610 SE
NB100-65611MFV610
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CD79B Antibody (HM79-11) [PE/Cy5.5] Summary

Immunogen
CD79 alpha/CD79 beta heterodimer purified from WEHI-231 B cells
Specificity
NB100-65611 recognizes murine CD79 beta, which is expressed by B cells as part of the B cell receptor complex (immunoglobulin and the CD79 alpha/beta heterodimer). Murine CD79 beta is expressed at the cell surface of pro-B cells prior to surface immunoglobulin, and is expressed throughout B cell differentiation. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
CD79B
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reactivity Notes

Reacts with Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for CD79B Antibody (HM79-11) [PE/Cy5.5]

  • B29
  • B29B-cell-specific glycoprotein B29
  • B-cell antigen receptor complex-associated protein beta chain
  • CD79B antigen (immunoglobulin-associated beta)
  • CD79b antigen
  • CD79b molecule, immunoglobulin-associated beta
  • CD79B
  • IGB
  • IGBAGM6
  • Ig-beta
  • Immunoglobulin-associated B29 protein

Background

Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79alpha/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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CD79b - A Signal Transduction Component of the B-cell Receptor
The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...  Read full blog post.
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Bioinformatics

Gene Symbol CD79B