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CD7 Antibody (MEM-186) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IP, CyTOF-ready
Clone
MEM-186
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB500-326AF350
Alexa Fluor 405
NB500-326AF405
Alexa Fluor 488
NB500-326AF488
Alexa Fluor 532
NB500-326AF532
Alexa Fluor 594
NB500-326AF594
Alexa Fluor 647
NB500-326AF647
Alexa Fluor 700
NB500-326AF700
Alexa Fluor 750
NB500-326AF750
Allophycocyanin
NB500-326APC
Allophycocyanin/Cy7
NB500-326APCCY7
Biotin
NB500-326B
CoraFluor 1
NB500-326CL1
DyLight 350
NB500-326UV
DyLight 405
NB500-326V
DyLight 488
NB500-326G
DyLight 550
NB500-326R
DyLight 594
NB500-326DL594
DyLight 650
NB500-326C
DyLight 680
NB500-326FR
DyLight 755
NB500-326IR
FITC
NB500-326F
HRP
NB500-326H
Janelia Fluor 525
NB500-326JF525
Janelia Fluor 549
NB500-326JF549
Janelia Fluor 585
NB500-326JF585
Janelia Fluor 635
NB500-326JF635
Janelia Fluor 669
NB500-326JF669
PE
NB500-326PE
PE/Atto594
NB500-326PEATT594
PE/Cy5.5
NB500-326PECY55
PE/Cy7
NB500-326PECY7
PerCP
NB500-326PCP
Unconjugated
NB500-326
mFluor Violet 450 SE
NB500-326MFV450
mFluor Violet 500 SE
NB500-326MFV500
mFluor Violet 610 SE
NB500-326MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB500-326
BSA Free
NB500-326
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CD7 Antibody (MEM-186) [Janelia Fluor® 646] Summary

Additional Information
Clone MEM-186 was used by HLDA to establish CD designation.
Immunogen
Human acute myelogenous leukaemia cell line KG-1.
Specificity
The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia. HLDA VI; WS Code T 6T-015
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CD7
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD7 Antibody (MEM-186) [Janelia Fluor® 646]

  • CD7 antigen (p41)
  • CD7 antigen
  • CD7 molecule
  • CD7
  • GP40T-cell surface antigen Leu-9
  • LEU-9
  • T-cell antigen CD7
  • T-cell leukemia antigen
  • Tp40
  • TP41
  • TP41p41 protein

Background

CD7, also known as gp40, is a 40 kD type I transmembrane glycoprotein member of the immunoglobulin superfamily. It is found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD7