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Caspase-7 Antibody (25B881.1) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
25B881.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56529AF350
Alexa Fluor 405
NB100-56529AF405
Alexa Fluor 488
NB100-56529AF488
Alexa Fluor 532
NB100-56529AF532
Alexa Fluor 594
NB100-56529AF594
Alexa Fluor 647
NB100-56529AF647
Alexa Fluor 700
NB100-56529AF700
Alexa Fluor 750
NB100-56529AF750
Biotin
NB100-56529B
CoraFluor 1
NB100-56529CL1
DyLight 350
NB100-56529UV
DyLight 405
NB100-56529V
DyLight 488
NB100-56529G
DyLight 550
NB100-56529R
DyLight 594
NB100-56529DL594
DyLight 650
NB100-56529C
DyLight 680
NB100-56529FR
DyLight 755
NB100-56529IR
FITC
NB100-56529F
HRP
NB100-56529H
Janelia Fluor 549
NB100-56529JF549
Janelia Fluor 585
NB100-56529JF585
Janelia Fluor 635
NB100-56529JF635
Janelia Fluor 646
NB100-56529JF646
Janelia Fluor 669
NB100-56529JF669
Unconjugated
NB100-56529
mFluor Violet 450 SE
NB100-56529MFV450
mFluor Violet 500 SE
NB100-56529MFV500
mFluor Violet 610 SE
NB100-56529MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56529
BSA Free
NB100-56529SS
BSA Free
NB100-56529
Azide and BSA Free
NBP2-80615
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Caspase-7 Antibody (25B881.1) [Janelia Fluor® 525] Summary

Immunogen
This antibody was generated against recombinant protein of active form of human Caspase-7.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CASP7
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Caspase-7 Antibody (25B881.1) [Janelia Fluor® 525]

  • apoptosis-related cysteine protease
  • Apoptotic protease Mch-3
  • CASP7
  • CASP-7
  • caspase 7, apoptosis-related cysteine peptidase
  • Caspase7
  • Caspase-7
  • EC 3.4.22
  • EC 3.4.22.60
  • ICE-like apoptotic protease 3
  • Lice2 alpha/beta/gamma
  • Mch3

Background

Caspase 7 (CASP7) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 7 is an executioner protein of apoptosis. It is activated upon cell death stimuli and induces apoptosis.

Caspase 7 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 7 form.

Caspase 7 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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By Rachel M.A. Linger, Ph.D.What is survivin?Survivin is a small (16.5 kDa) protein normally found in human fetal tissue. In contrast, survivin is typically undetectable in most normal adult tissues. Expression of ...  Read full blog post.
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Bioinformatics

Gene Symbol CASP7