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Caspase-11 Antibody (8A5) [Biotin]

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Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, IP
Clone
8A5
Clonality
Monoclonal
Host
Rat
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-80099AF350
Alexa Fluor 405
NBP2-80099AF405
Alexa Fluor 488
NBP2-80099AF488
Alexa Fluor 532
NBP2-80099AF532
Alexa Fluor 594
NBP2-80099AF594
Alexa Fluor 647
NBP2-80099AF647
Alexa Fluor 700
NBP2-80099AF700
Alexa Fluor 750
NBP2-80099AF750
Allophycocyanin
NBP2-80099APC
CoraFluor 1
NBP2-80099CL1
DyLight 350
NBP2-80099UV
DyLight 405
NBP2-80099V
DyLight 488
NBP2-80099G
DyLight 550
NBP2-80099R
DyLight 594
NBP2-80099DL594
DyLight 650
NBP2-80099C
DyLight 680
NBP2-80099FR
DyLight 755
NBP2-80099IR
FITC
NBP2-80099F
HRP
NBP2-80099H
Janelia Fluor 525
NBP2-80099JF525
Janelia Fluor 549
NBP2-80099JF549
Janelia Fluor 646
NBP2-80099JF646
Janelia Fluor 669
NBP2-80099JF669
PE
NBP2-80099PE
PerCP
NBP2-80099PCP
Unconjugated
NBP2-80099
mFluor Violet 450 SE
NBP2-80099MFV450
mFluor Violet 500 SE
NBP2-80099MFV500
mFluor Violet 610 SE
NBP2-80099MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-80099
BSA Free
NBP2-80099
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Caspase-11 Antibody (8A5) [Biotin] Summary

Immunogen
Recombinant mouse caspase-11 (p20 fragment).
Specificity
Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38kDa and ~43kDa by Western blot.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Rat
Gene
Casp4
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Caspase-11 Antibody (8A5) [Biotin]

  • ich-3
  • CASP11
  • CASP-11
  • CASP4
  • CASP-4
  • caspase 4, apoptosis-related cysteine peptidase
  • Caspl

Background

Caspase-11 (also known as CASP11, CASP4, and ich-3) is one of several different types of caspases. The general role of caspases is to assist in cell death as well as inflammation. More specifically, caspase-11 is involved with pyroptotic cell death. Its structure is heterotrimeric, consisting of two antiparallel heterodimers. Novus offers Caspase 11 antibodies, Peptides and Proteins, Lysates, and RNAi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Caspase-11 Products

Blogs on Caspase-11.

Check out the latest blog posts on Caspase-11.
The NLRP3 Inflammasome: Macrophage Activator & Pathology Driver
By Victoria Osinski, PhDWhat is the NLRP3 Inflammasome?With its critical role in innate immunity, the nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome ...  Read full blog post.
Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release
By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...  Read full blog post.
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While known for their role in programmed cell death, caspases are also essential for mediating inflammatory responses and innate immunity. Binding of microbial molecules by pattern recognition receptors triggers the formation of the multiprotein in...  Read full blog post.
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Bioinformatics

Gene Symbol Casp4