BRD3 Antibody (6E7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The bromodomain is a conserved 110 amino acid motif which specifically interacts with acetyl lysines, at least in the context of short histone H3 and H4 peptides. Although bromodomains have now been found in more than 40 different proteins, the function of this motif is poorly understood. The association of two N terminal bromodomains with a C terminal extraterminal (ET) domain defines the Fsh/Brd subgroup, which includes members in many species. In vertebrates, four members of the Fsh/Brd subgroup have now been identified: Brd2/RING3/fsrg1, Brd3/ORFX/fsrg2, Brd4/HUNK1/MCAP, and Brd5/BRDT. The Brd3/ORFX gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.

Showing Publication 1 - 1 of 1.

Publication using H00008019-M01	Applications	Species
Hsu PL, Chien CW, Tang YA et al. Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis Science advances 2023-04-14 [PMID: 37043564] (IHC, Human)	IHC	Human

Array H00008019-M01

• BRD3 Antibodies
• BRD3 Lysate
• BRD3 Proteins