BIN1 Antibody (99F) [DyLight 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, DB, ELISA, ICC/IF, IP
Clone
99F
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

BIN1 Antibody (99F) [DyLight 350] Summary

Immunogen
BIN1 Antibody (99F) was produced in mouse by repeated immunizations with BIN1 polypeptide followed by hybridoma development. (Uniprot: O00499)
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
BIN1
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Dot Blot
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Cross-reactivity with BIN1 from other sources has not been determined

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BIN1 Antibody (99F) [DyLight 350]

  • AMPH2
  • Amphiphysin II
  • Amphiphysin-like protein
  • AMPHLDKFZp547F068
  • box dependant MYC interacting protein 1
  • bridging integrator 1Box-dependent myc-interacting protein 1
  • MGC10367
  • myc box-dependent-interacting protein 1
  • SH3P9

Background

BIN1 encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BIN1 Antibody (NBP2-21674UV) (0)

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Secondary Antibodies

 

Isotype Controls

Additional BIN1 Products

Research Areas for BIN1 Antibody (NBP2-21674UV)

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Blogs on BIN1

There are no specific blogs for BIN1, but you can read our latest blog posts.
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Contact Information

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Calculators

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Bioinformatics

Gene Symbol BIN1