beta-1 Adrenergic R/ADRB1 Antibody (2203D) [Unconjugated] Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Synthetic peptide containing human beta ‑1 Adrenergic R/ADRB1 Accession # P08588 |
Specificity |
Detects human beta ‑1 Adrenergic R/ADRB1 in direct ELISAs.
|
Source |
N/A |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for beta-1 Adrenergic R/ADRB1 Antibody (2203D) [Unconjugated]
Background
The beta-1 Adrenergic Receptor (ADRB1) is a 477 aminoacids
long and seven-transmembrane domain protein that belongs to the G
protein-coupled receptor (GPCR) 1 family. The adrenergic receptors, including
ADRB1, are a prototypic family of guanine nucleotide binding regulatory
protein-coupled receptors that mediate the physiological effects of the hormone
epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine
and norepinephrine with approximately equal affinity. ADRB1 is localized at the
plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and
coiled-coil motif-containing protein (GOPC) overexpression.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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