Mouse BDNF ELISA Kit (Colorimetric)

This product is produced by and distributed for Abnova, a company based in Taiwan.

FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family. BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ELISA.

Showing Publications 1 - 10 of 20. Show All 20 Publications. Collapse Publications.

Publications using KA0331	Applications	Species
Badmus OO, Kipp ZA, Bates EA et al. The loss of hepatic PPAR? in mice causes hypertension and cardiovascular disease American journal of physiology. Regulatory, integrative and comparative physiology 2023-05-22 [PMID: 37212551] (ELISA)	ELISA
Alessia D, Laura M, Francesca G et al. Palmitoylethanolamide Modulation of Microglia Activation: Characterization of Mechanisms of Action and Implication for Its Neuroprotective Effects. Int J Mol Sci. 2021-03-17 [PMID: 33802689]
Shamsudheen M, Michael B, David T et al. Glycogen synthase kinase-3 inhibition rescues sex-dependent contextual fear memory deficit in HIV-1 transgenic mice. Br J Pharmacol. 2020-11-23 [PMID: 33080056]
Mohit K, Sahabuddin A, Basveshwar G et al. Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-?B, p38 MAPK/JNK, Nrf2/ARE signaling. Neurochem Int. 2020-08-24 [PMID: 32853749]
Shirin B, Nora A, Shyama N et al. Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type. Transl Stroke Res. 2020-05-06 [PMID: 32378029]
Yue Y, Xue Q, Yang J et al. Wnt-activated olfactory ensheathing cells stimulate neural stem cell proliferation and neuronal differentiation Brain Res. 2020-02-10 [PMID: 32057808] (ELISA, Mouse)	ELISA	Mouse
Mukesh V, Nancy Y, Shintaro K et al. Motor function deficits in the estrogen receptor beta knockout mouse: Role on excitatory neurotransmission and myelination in the motor cortex. Neuroendocrinology. 2020-01-28 [PMID: 31991411]
Wu C, Chen C, Hung T et al. Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage. J Biomed Sci. 2019-07-15 [PMID: 31307481]
Laio T, Chen C, Tsou H et al. Acute and Chronic Exposure of Toluene Induces Genotoxicity in Different Regions of the Brain in Normal and Allergic Mouse Models. Neurotox Res. 2019-03-19 [PMID: 30888611]
A Bodur, ? ?nce, C Kahraman, ? Abidin, S Aydin-Abid, A Alver Chronically reduced BDNF levels increase oxidative stress in epididymal, but not subcutaneous, adipose tissue following high sucrose and high fat diets fed mice Arch. Biochem. Biophys., 2019-02-21;0(0):. 2019-02-21 [PMID: 30797748]
Zhang H, Zhang C, Vincent J et al. Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models. Nat Commun. 2018-10-15 [PMID: 30323233]
Harris NM, Ritzel R, Mancini N et al. Nano-particle delivery of brain derived neurotrophic factor after focal cerebral ischemia reduces tissue injury and enhances behavioral recovery. Pharmacol Biochem Behav 2016-09-09 [PMID: 27619636]
Klaren RE, Stasula U, Steelman AJ et al. Effects of exercise in a relapsing-remitting model of experimental autoimmune encephalomyelitis. J Neurosci Res 2016-10-01 [PMID: 27312674]
Dekeyster E, Geeraerts E, Buyens T et al. Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB. PLoS One. 2015-11-11 [PMID: 26560713]
Sumida M, Hane M, Yabe U et al. Rapid trimming of cell surface polySia by exovesicular sialidase triggers release of preexisting surface neurotrophin. J Biol Chem. 2015-05-22 [PMID: 25750127]
Wu CH, Hung TH, Chen CC et al. Post-Injury Treatment with 7,8-Dihydroxyflavone, a TrkB Receptor Agonist, Protects against Experimental Traumatic Brain Injury via PI3K/Akt Signaling. PLoS One. 2014-11-21 [PMID: 25415296]
Nuytens K, Gantois I, Stijnen P et al. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiol Dis. 2012-11-12 [PMID: 23153818]
Kovalchuk Y, Hanse E, Kafitz KW et al. Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science 2002-03-01 [PMID: 11872844]
Lyons WE, Mamounas LA, Ricaurte GA et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci U S A 1999-12-21 [PMID: 10611369]
Jones KR, Reichardt LF. Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc Natl Acad Sci U S A. 1990-10-01 [PMID: 2236018]
Show All 20 Publications. Collapse Publications.

Array KA0331

• BDNF Antibodies
• BDNF ELISA Kits
• BDNF Lysates
• BDNF Proteins
• BDNF Proteins and Enzymes
• BDNF ELISAs