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BACE-2 Antibody (1/ 9) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
1/ 9
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-81075AF350
Alexa Fluor 405
NBP2-81075AF405
Alexa Fluor 488
NBP2-81075AF488
Alexa Fluor 532
NBP2-81075AF532
Alexa Fluor 594
NBP2-81075AF594
Alexa Fluor 647
NBP2-81075AF647
Alexa Fluor 700
NBP2-81075AF700
Alexa Fluor 750
NBP2-81075AF750
Biotin
NBP2-81075B
CoraFluor 1
NBP2-81075CL1
DyLight 405
NBP2-81075V
DyLight 488
NBP2-81075G
DyLight 550
NBP2-81075R
DyLight 594
NBP2-81075DL594
DyLight 650
NBP2-81075C
DyLight 680
NBP2-81075FR
DyLight 755
NBP2-81075IR
FITC
NBP2-81075F
HRP
NBP2-81075H
Janelia Fluor 525
NBP2-81075JF525
Janelia Fluor 549
NBP2-81075JF549
Janelia Fluor 585
NBP2-81075JF585
Janelia Fluor 635
NBP2-81075JF635
Janelia Fluor 646
NBP2-81075JF646
Janelia Fluor 669
NBP2-81075JF669
PerCP
NBP2-81075PCP
Unconjugated
NBP2-81075-0.2mg
mFluor Violet 450 SE
NBP2-81075MFV450
mFluor Violet 500 SE
NBP2-81075MFV500
mFluor Violet 610 SE
NBP2-81075MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81075-0.2mg
Azide and BSA Free
NBP2-81075-0.2mg
Azide and BSA Free
NBP2-81075-0.025mg
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BACE-2 Antibody (1/ 9) [DyLight 350] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Human BACE-2 244-333.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BACE2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BACE-2 Antibody (1/ 9) [DyLight 350]

  • AEPLC
  • Asp 1
  • ASP1
  • ASP21
  • Aspartic-like protease 56 kDa
  • Aspartyl protease 1
  • BACE2
  • BACE-2
  • beta secretase 2
  • beta-secretase 2
  • beta-site amyloid beta A4 precursor protein-cleaving enzyme 2
  • Beta-site amyloid precursor protein cleaving enzyme 2
  • Beta-site APP cleaving enzyme 2
  • beta-site APP-cleaving enzyme 2
  • beta-site APP-cleaving enzyme 2, EC 3.4.2310ALP5656 kDa aspartic-like protease
  • CEAP1
  • Down region aspartic protease
  • Down syndrome region aspartic protease
  • DRAPBAE2
  • EC 3.4.23
  • EC 3.4.23.45
  • memapsin-1
  • Membrane-associated aspartic protease 1
  • theta-secretase
  • transmembrane aspartic proteinase Asp1

Background

BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BACE2