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Apolipoprotein A-I/ApoA1 Antibody (2083A) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, Flow, ICC/IF
Clone
2083A
Clonality
Monoclonal
Host
Rabbit
Conjugate
FITC

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Apolipoprotein A-I/ApoA1 Antibody (2083A) [FITC] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
E. coli-derived recombinant human ApoA1
Asp25-Gln267
Accession # P02647
Specificity
Detects human ApoA1 in direct ELISAs and Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for Apolipoprotein A-I/ApoA1 Antibody (2083A) [FITC]

  • Alp-1
  • APOA1
  • Apo-AI
  • apoA-I
  • Apolipoprotein A1
  • Apolipoprotein AI
  • Apolipoprotein A-I
  • Brp-14
  • Ltw-1
  • Lvtw-1
  • MGC117399
  • Sep-1
  • Sep-2

Background

Apolipoprotein A1 (apo A1) is the major polypeptide of the human plasma high density lipoprotein (HDL). The structure and function of the apo A1 gene are of interest because of the inverse correlation shown between HDL levels and coronary heart disease (1). The 267 amino acid precursor initially undergoes intracellular co-translational proteolytic cleavage into proapoA-I. ProapoA-I is secreted from the cell and was isolated from thoracic duct lymph in the apoA-I1 isoform position. Results indicate that apo A1 is present in human plasma, and undergoes post-translational proteolytic cleavage to mature plasma apoA-I (2). Cleavage of this protein with cyanogen bromide yields four fragments designated in the order of elution from Bio-Gel P-30 as CNBr I, II, III, and IV (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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