APLP-1 Antibody [Biotin] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse APLP-1 Gly37-Arg582 Accession # Q03157 |
Specificity |
Detects mouse APLP-1 in Western blots. In Western blots, approximately 45% cross-reactivity with recombinant human APLP-1 is observed and less than 1% cross-reactivity with recombinant mouse APLP-2 is observed. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
DPP4 |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for APLP-1 Antibody [Biotin]
Background
APLP-1 is a transmembrane metalloprotein that is expressed in central
neurons. Similar to APP and APLP-2, APLP-1 is susceptible to cleavage
by various secretases, generating multiple fragments from the
extracellular and intracellular domains. These include peptides similar
to the amyloidogenic A beta peptides and a cytoplasmic fragment that
associates with Fe65 family proteins and functions as a transcriptional
activator. The extracellular domain contains heparin and collagen
binding regions and is 89% identical between human and mouse.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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