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Aminopeptidase A/ENPEP Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

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Aminopeptidase A/ENPEP Antibody [Janelia Fluor® 646] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Mouse Aminopeptidase A/ENPEP (Uniprot#: P16406; Arg41-Pro945).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ENPEP
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Aminopeptidase A/ENPEP Antibody [Janelia Fluor® 646]

  • Aminopeptidase A
  • APA
  • AP-A
  • CD249 antigen
  • CD249
  • Differentiation antigen gp160
  • EAP
  • EC 3.4.11
  • EC 3.4.11.7
  • ENPEP
  • glutamyl aminopeptidase (aminopeptidase A)
  • glutamyl aminopeptidase
  • gp160

Background

Aminopeptidase A is a zinc-dependent metallopeptidase that selectively cleaves N-terminal Glu, or Asp residues from peptides. In mice, it is expressed on early B cells and on a subset of thymic cortical epithelial cells, but not on mature lymphocytes. Additionally, it is expressed on endothelial cells, intestinal epithelium, proximal renal tubules, and other non-hemopoietic tissues. In humans, angiotensin II is the the best-defined biologically active substrate of APA. Although its role in the immune response is still uncertain, its expression on renal cell carcinoma has been the focus of some cancer research studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ENPEP