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AlphaB Crystallin/CRYAB Antibody (3A10.C9) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity Hu, Rt, BvSpecies Glossary
Applications ELISA, IHC, MA
Clone
3A10.C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

AlphaB Crystallin/CRYAB Antibody (3A10.C9) [Alexa Fluor® 405] Summary

Immunogen
Native Alpha B Crystallin
Localization
Cytoplasm , Nucleus
Specificity
Detects approx 20kDa (predicted mol.weight is approx 21kDa). Does not cross-react with alpha A-crystallin, Beta L-crystallin, Beta H-crystallin, gamma-crystallin, HSP25, HSP27 or HSP47 proteins.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CRYAB
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Microarray
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for AlphaB Crystallin/CRYAB Antibody (3A10.C9) [Alexa Fluor® 405]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • CRYAB
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component

Background

Crystallin AB is a member of the small heat shock protein family and expressed in several tissues including brain, kidney cardiac and skeletal muscle. Crystallin AB functions as a molecular chaperone and in intracellular architecture. Crystallin AB has shown to have interactions with CRYAA, CRYGC, CRYBB2, CRYBA1 and HSPB8. Defects in crystalline AB have been linked to cause myopathy myofibrillar type 2, cataract posterior polar type 2, and myopathy myofibrillar fatal infantile hypertonic alpha-B crystallin-related (MFMFIH-CRYAB).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRYAB
Entrez
Uniprot