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alpha-2C Adrenergic R/ADRA2C Antibody (S330A-80) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clone
S330A-80
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

alpha-2C Adrenergic R/ADRA2C Antibody (S330A-80) [Alexa Fluor® 405] Summary

Immunogen
Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
Localization
Cell Membrane
Specificity
Detects 50kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADRA2C
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for alpha-2C Adrenergic R/ADRA2C Antibody (S330A-80) [Alexa Fluor® 405]

  • a-2C AdrenergicR
  • ADRA2C
  • ADRA2L2
  • ADRA2L2alpha-2CAR
  • ADRA2RL2
  • ADRARL2
  • adrenergic, alpha-2C-, receptor
  • Alpha-2 adrenergic receptor subtype C4
  • alpha2-AR-C4
  • alpha-2C Adrenergic R
  • alpha-2C adrenergic receptor
  • alpha2C AdrenergicR
  • Alpha-2C adrenoceptor
  • Alpha-2C adrenoreceptor
  • alpha-2C-adrenergic receptor
  • ALPHA2CAR
  • Alpha-2CAR

Background

The alpha-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. There are 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha2C is required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADRA2C