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ALDH4A1 Antibody (002) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clone
002
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

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ALDH4A1 Antibody (002) [DyLight 488] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human ALDH4A1 (Accession#: AAH07581.1; Lys25-Gln563).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ALDH4A1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ALDH4A1 Antibody (002) [DyLight 488]

  • aldehyde dehydrogenase 4 family, member A1
  • Aldehyde dehydrogenase family 4 member A1
  • ALDH4DKFZp779M035
  • delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
  • EC 1.5.1.12
  • mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
  • P5C dehydrogenase
  • P5CD
  • P5CDH

Background

ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Two transcript variants encoding the same protein have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ALDH4A1