AGTR-1 Antibody

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 2 of 2.

Publications using NB100-57073	Applications	Species
Marut W, Kavian N, Servettaz A et al. Amelioration of Systemic Fibrosis in Mice by Angiotensin II Receptor Blockade. Arthritis Rheum 2013-05-01 [PMID: 23335130] (IF/IHC, Mouse)	IF/IHC	Mouse
Wang M, Jiang C, Wang C, Yao Q. The Role of brain angiotensinergic AT(1) receptor in the carbachol-induced natriuresis and expression of nNOS in the Locus Coeruleus (LC) and proximal convoluted tubule (PCT). Physiol Res 2006-08-22 [PMID: 16925472]

Images	Ratings	Applications	Species	Date	Details
	1 reviewed by: Kristine DeLeon-Pennell	WB	Mouse	11/30/2016	View Summary Application Western Blot Sample Tested cardiac tissue Species Mouse

Array NB100-57073

• AGTR-1 Antibodies
• AGTR-1 ELISA Kits
• AGTR-1 Lysates
• AGTR-1 Proteins