AGTR-1 Products

Description

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Bioinformatics

Entrez	11607 Mouse 185 Human 24180 Rat
Uniprot	AAH22447 Human D3DNG8 Human EAW78909 Human NP_000676.1 Human NP_004826 Human NP_114038 Human NP_114438 Human P30556 Human
Product By Gene ID	185
Alternate Names	AG2S AGTR1AAngiotensin II type-1 receptor Angiostensin Receptor angiotensin II receptor, type 1 angiotensin receptor 1 angiotensin receptor 1B AT1AT1AR AT1B AT1R AT2R1A AT2R1AGTR1B AT2R1BAT1BR HAT1R type-1 angiotensin II receptor type-1B angiotensin II receptor