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Megakaryocyte Development Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Megakaryocyte Development Pathway and Polyploidy, Leukemia, Thrombocytosis, Acute Megakaryocytic Leukemias, Endoreduplication. The study of the Megakaryocyte Development Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Megakaryocyte Development Pathway has been researched in relation to Cell Cycle, Platelet Formation, Megakaryocyte Differentiation, Cell Proliferation, Cell Development. The Megakaryocyte Development Pathway complements our catalog of research reagents including antibodies and ELISA kits against GM-CSF, ACHE, CD34, CDKN1A, CSF2.

Top Research Reagents

We have 3758 products for the study of the Megakaryocyte Development Pathway that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

IL-6 [HRP]
D6050B
N/A IL-6 [HRP]N/A IL-6 [HRP]


Species Human

782 Publications
Acetylcholinesterase/ACHE Antibody
NBP1-31329
Western Blot: Acetylcholinesterase/ACHE Antibody [NBP1-31329] - Various tissue extracts (50 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AChE antibody diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Acetylcholinesterase/ACHE Antibody [NBP1-31329] - DIV9 rat hippocampal neuron and Glia cell cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: AChE stained by AChE antibody diluted at 1:500.Red: Tau, a Axon marker, stained by Tau antibody [287] diluted at 1:500.Blue: Fluoroshield with DAPI.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

GATA-1 Antibody (4F5) - BSA Free
NBP1-47492
Western Blot: GATA-1 Antibody (4F5) [NBP1-47492] - Analysis using GATA1 mouse mAb against K562 (1) cell lysate.Immunocytochemistry/Immunofluorescence: GATA-1 Antibody (4F5) [NBP1-47492] - Analysis of K562(left) cells using GATA1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human, Baboon
Applications WB, ELISA, ICC/IF

     1 Review

2 Publications
CD34 Antibody (MEC 14.7)
NB600-1071
Immunocytochemistry/Immunofluorescence: CD34 Antibody (MEC 14.7) [NB600-1071] - CD34 antibody was tested in WEHI-3 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).Immunohistochemistry-Paraffin: CD34 Antibody (MEC 14.7) [NB600-1071] - Analysis of a FFPE tissue section of mouse small intestine using rat anti-mouse CD34 (clone MEC 14.7) at 1:100 dilution. The signal was developed using HRP-conjugated anti-rat secondary with DAB reagent which followed counterstaining of nuclei using hematoxylin. This antibody specifically labelled the endothelial cells in blood vessels located primarily in the sub-mucosa, and of that of the mucosa muscularis and the mucosal lacteal.

Rat Monoclonal
Species Mouse, Human (Negative)
Applications WB, ELISA, Flow

29 Publications
Thyroid Peroxidase Antibody
NBP1-80670
Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining in human thyroid gland and cerebral cortex tissues using anti-TPO antibody. Corresponding TPO RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining of human cerebral cortex shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

4 Publications
Nuclear Factor Erythroid Derived 2 Antibody
NBP1-82580
Immunohistochemistry-Paraffin: Nuclear Factor Erythroid Derived 2 Antibody [NBP1-82580] - Staining in human bone marrow and liver tissues . Corresponding NFE2 RNA-seq data are presented for the same tissues.Western Blot: Nuclear Factor Erythroid Derived 2 Antibody [NBP1-82580] - Analysis in control (vector only transfected HEK293T lysate) and NFE2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IHC

p21/CIP1/CDKN1A Antibody (WA-1)
NBP2-29463
Immunohistochemistry-Paraffin: p21/CIP1/CDKN1A Antibody (WA-1) [NBP2-29463] - Formalin-fixed, paraffin-embedded human bladder carcinoma stained with p21 Monoclonal Antibody (WA-1).

Mouse Monoclonal
Species Human, Mouse, Chimpanzee
Applications WB, Flow, ICC/IF

24 Publications
Thrombopoietin R/Tpo R Antibody [Unconjugated]
AF1016
Simple Western lane view shows lysates of Daudi human Burkitt's lymphoma cell line, loaded at 0.2 mg/mL. A specific band was detected for Thrombopoietin R/Tpo R at approximately 73 kDa (as indicated) using 20 µg/mL of Goat Anti-Human Thrombopoietin R/Tpo R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1016) . This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.Measured by its ability to neutralize Thrombopoietin/Tpo-induced proliferation in the MO7e human megakaryocytic leukemic cell line. Avanzi, G. et al. (1988) Br. J. Haematol. 69:359. The Neutralization Dose (ND<sub>50</sub>) is typically 0.100‑1.50 μg/mL in the presence of 10 ng/mL Recombinant Human Thrombopoietin/Tpo.

Goat Polyclonal
Species Human
Applications WB, Simple Western, Neut

4 Publications
Midkine Antibody [Unconjugated]
AF-258-PB
Western blot shows lysates of SH-SY5Y human neuroblastoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human Midkine Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-258-PB) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=Midkine was detected in immersion fixed paraffin-embedded sections of human prostate using Goat Anti-Human Midkine Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-258-PB) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (<a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

9 Publications
Integrin alpha 2b/CD41 Antibody (745201) [Unconjugated]
MAB7616
Western blot shows lysates of human platelets. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Integrin a2b/CD41 Monoclonal Antibody (Catalog # MAB7616) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (<a class=Human peripheral blood platelets were stained with Fluorescein-conjugated Anti-Mouse Integrin alpha 2b/CD41 (Clone P2) and either (A) Mouse IgG<SUB>1</SUB> Isotype Control (Catalog # <A class=NoLineLink href=

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

6 Publications
Erythropoietin/EPO [HRP]
MEP00B
N/A Erythropoietin/EPO [HRP]N/A Erythropoietin/EPO [HRP]


Species Mouse
Applications ELISA

105 Publications
CXCL4/PF4 [Biotin]
DY795
N/A CXCL4/PF4 [Biotin]


Species Human
Applications ELISA

26 Publications
IL-11 [HRP]
D1100
N/A IL-11 [HRP]N/A IL-11 [HRP]


Species Human
Applications ELISA

31 Publications
Thrombopoietin/THPO [Unconjugated]
288-TPN/CF
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED<sub>50</sub> for this effect is 5-15 ng/mL.


Species Human
Applications BA

12 Publications
IL-3 [Unconjugated]
203-IL
Recombinant Human IL-3 Protein (Catalog # 203-IL) has a molecular weight (MW) of 14.6 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer. Recombinant Human IL-3 (Catalog # 203-IL) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 0.02-0.1 ng/mL.


Species Human
Applications BA

218 Publications
SCF/c-kit Ligand [Unconjugated]
255-SC


Species Human
Applications BA

203 Publications
GM-CSF [Unconjugated]
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
ZFPM1 Antibody
NBP2-47572
Immunocytochemistry/Immunofluorescence: ZFPM1 Antibody [NBP2-47572] - Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm, cytosol & vesicles.Immunohistochemistry-Paraffin: ZFPM1 Antibody [NBP2-47572] - Staining of human stomach shows high expression.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

MVK Antibody (2C5)
H00004598-M02
Western Blot: MVK Antibody (2C5) [H00004598-M02] - Analysis of MVK expression in transfected 293T cell line by MVK monoclonal antibody (M02), clone 2C5.Lane 1: MVK transfected lysate(42.451 KDa).Lane 2: Non-transfected lysate.Immunohistochemistry-Paraffin: MVK Antibody (2C5) [H00004598-M02] - Analysis of monoclonal antibody to MVK on formalin-fixed paraffin-embedded human salivary gland. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC