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Exfoliation Syndrome: Disease Bioinformatics

Research of Exfoliation Syndrome has been linked to Glaucoma, Intraocular Pressure Disorder, Glaucoma, Open-angle, Cataract, Primary Open Angle Glaucoma. The study of Exfoliation Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Exfoliation Syndrome include Pathogenesis, Pigmentation, Dehiscence, Localization, Aging. These pathways complement our catalog of research reagents for the study of Exfoliation Syndrome including antibodies and ELISA kits against CCT, HNK-1, TRABECULAR MESHWORK-INDUCED GLUCOCORTICOID RESPONS, PG, BRCA1.

Top Research Reagents

We have 2848 products for the study of Exfoliation Syndrome that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free
NBP1-19788
Immunocytochemistry/Immunofluorescence: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [NBP1-19788] - Antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).Immunohistochemistry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [NBP1-19788] - Analysis in mouse brain using DAB with hematoxylin counterstain.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-P

1 Publication
AP3B1 Antibody
NBP3-38363
Immunohistochemistry: AP3B1 Antibody [NBP3-38363] - Immunohistochemistry analysis of paraffin-embedded Human breast cancer using AP3B1 Rabbit pAb at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.Western Blot: AP3B1 Antibody [NBP3-38363] - Western blot analysis of various lysates using AP3B1 Rabbit pAb at 1:1000 dilution.<br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

PEX19 Antibody
NBP1-32925
Immunocytochemistry/Immunofluorescence: PEX19 Antibody [NBP1-32925] - Methanol-fixed HeLa antibody (Green) at 1:500 dilution.Immunohistochemistry-Paraffin: PEX19 Antibody [NBP1-32925] - Rat liver. PEX19 stained by PEX19 antibody diluted at 1:1000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

PGD2 Synthase/PTGDS Antibody
NBP1-79280
Western Blot: PGD2 Synthase/PTGDS Antibody [NBP1-79280] - Titration: 1 ug/ml Positive Control: HepG2 cell lysate.Immunohistochemistry-Paraffin: PGD2 Synthase/PTGDS Antibody [NBP1-79280] - Staining of mouse brain . Image provided by Allison Brager - Department of Neurobiology, Morehouse School of Medicine.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

3 Publications
SLC26A4 Antibody
NBP1-85237
Immunohistochemistry-Paraffin: SLC26A4 Antibody [NBP1-85237] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.Immunohistochemistry-Paraffin: SLC26A4 Antibody [NBP1-85237] - Staining of human thyroid gland shows weak to moderate cytoplasmic and membranous positivity in follicle cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-Fr, IHC-P

     1 Review

2 Publications
BRCA1 Antibody (RAY) - BSA Free
NB100-598
Western Blot: BRCA1 Antibody (RAY) [NB100-598] - Analysis of BRCA1 on MCF7 lysate.Immunocytochemistry/Immunofluorescence: BRCA1 Antibody (RAY) [NB100-598] - BRCA (RAY) antibody was tested in MCF-7 cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

6 Publications
Elastin Antibody (BA-4)
NB100-2076
Western Blot: Elastin Antibody (BA-4) [NB100-2076] - Analysis of tropoelastin using the mAb BA-4 elastin antibody (NB100-2076). A: Western blot of tropoelastin purified from bovine ligamentum nuchae tissue minces. B: Autoradiogram of a gradient SDS-polyacrylamide gel showing [3H] leucine-labeled tropoelasti.Immunohistochemistry-Paraffin: Elastin Antibody (BA-4) [NB100-2076] - Formalin fixed paraffin embedded human renal cell carcinoma stained with Elastin antibody (NB100-2076)

Mouse Monoclonal
Species Human, Bovine, Feline
Applications WB, ICC/IF, IHC

     2 Reviews

11 Publications
Prolyl Oligopeptidase/PREP Antibody
NBP2-33950
Immunocytochemistry/Immunofluorescence: Prolyl Oligopeptidase/PREP Antibody [NBP2-33950] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol. Antibody stainin is shown in green. Immunohistochemistry-Paraffin: Prolyl Oligopeptidase/PREP Antibody [NBP2-33950] - Staining of human pancreas shows low expression as expected.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

3 Publications
Clusterin/APOJ Antibody [Unconjugated]
AF2747
Clusterin was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse Clusterin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2747) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=Clusterin was detected in perfusion fixed frozen sections of mouse intestine using Goat Anti-Mouse Clusterin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2747) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, IHC, IP

13 Publications
Myocilin Antibody (297817) [Unconjugated]
MAB3446
Myocilin was detected in immersion fixed paraffin-embedded sections of Human Skeletal Muscle using Mouse Anti-Human Myocilin Monoclonal Antibody (Catalog # MAB3446) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=NoLineLink href=TMSCs reduce the Myoc retention in the TM tissue, promote the Myoc secretion into the aqueous humor, and reverse the ECM expression in the Tg-MyocY437H mice.(A) Immunofluorescent staining shows accumulated Myoc in the TM, iris, and ciliary body of the Tg and Tg-sham mice. TMSC transplantation alleviated the aggregation of Myoc in the TM, similar to the WT mice. Scale bars, 50 mm. Western blotting results show: (B) The representative bands of Myoc expression in the mouse limbal tissue and the relative Myoc protein levels with b-actin as internal control (n=5). (C) The representative bands of Myoc expression in the mouse aqueous humor and the relative Myoc protein levels with b-actin as internal control (n=5). (D) The representative bands of the expression of ECM components fibronectin (FN), collagen IV, and elastin in the limbal tissue and the relative ECM protein levels with b-actin as internal control (n=4-6). Data are presented as mean ± SD. One-way ANOVA (B,C) or two-way ANOVA (D) followed by Tukey’s multiple comparisons test. C: cornea, SC: Schlemm’s canal, TM: trabecular meshwork.Figure 5—source data 1.Relative myocilin protein levels in the corneal limbus for Figure 5B.Relative myocilin protein levels in the aqueous humor of each eye for Figure 5C; Relative extracellular mactrix protein levels in the corneal limbus for Figure 5D.Relative myocilin protein levels in the corneal limbus for Figure 5B.Relative myocilin protein levels in the aqueous humor of each eye for Figure 5C; Relative extracellular mactrix protein levels in the corneal limbus for Figure 5D. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/33506763), licensed under a CC-BY license. Not internally tested by R&D Systems.

Mouse Monoclonal
Species Human
Applications IHC

     1 Review

14 Publications
MTHFR Antibody (5D3) - BSA Free
NBP2-37607
Western Blot: MTHFR Antibody (5D3) [NBP2-37607] - Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.Immunohistochemistry-Paraffin: MTHFR Antibody (5D3) [NBP2-37607] - Analysis of intima cancer tissues (left) and prostate tissues (right) using MTHFR mouse mAb with DAB staining.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, IHC

LOXL1 Antibody
H00004016-D01P
Western Blot: LOXL1 Antibody [H00004016-D01P] - Analysis of LOXL1 expression in transfected 293T cell line by LOXL1 polyclonal antibody.Lane 1: LOXL1 transfected lysate(63.10 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: LOXL1 Antibody [H00004016-D01P] - Analysis of antibody to LOXL1 on HeLa cell. Antibody concentration 10 ug/ml.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

6 Publications
VEGF [HRP]
DVE00
N/A VEGF [HRP]N/A VEGF [HRP]


Species Human
Applications ELISA

686 Publications
TIMP-1 [HRP]
DTM100
N/A TIMP-1 [HRP]N/A TIMP-1 [HRP]


Species Human
Applications ELISA

97 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

821 Publications
PHEX
8090-ZN


Species Human
Applications EnzAct


Related Genes

Exfoliation Syndrome has been researched against:

Related Pathways

Exfoliation Syndrome has been linked to:

Related Diseases

Exfoliation Syndrome has been studied in relation to diseases such as:

Related PTMs

Exfoliation Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Exfoliation Syndrome is also known as exfoliation syndrome, pseudoexfoliation glaucoma, pseudoexfoliation syndrome, pseudoexfoliation glaucoma (disorder).