Rad1 Products

Description

Human Rad1 is a component of a heterotrimeric PCNA-like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.

Bioinformatics

Entrez	5810 Human
Uniprot	AAH06837 Human NM_002853 Human NP_002844 Human NP_002844.1 Human O60671 Human
Product By Gene ID	5810
Alternate Names	cell cycle checkpoint protein Hrad1 checkpoint control protein HRAD1 DNA repair exonuclease rad1 homolog DNA repair exonuclease REC1 EC 3.1.11.2 exonuclease homolog RAD1 hRAD1 HRAD1 RAD1 (S. pombe) homolog RAD1 homolog (S. pombe) Rad1-like DNA damage checkpoint protein REC1cell cycle checkpoint protein RAD1

Research Areas for Rad1

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Signal Transduction