Species: Hu
Applications: WB, IHC, ChIP
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: IHC, IP, WB (-)
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
REST, which is short for RE1-silencing transcription factor, locks down neuronal genes in other cells by grabbing onto the DNA and cementing in other molecules, an arrangement that stays intact as non-neuronal cells differentiate into liver, muscle, and other tissues. REST uses a different temporary off mechanism to direct neuronal development. REST is a tumor suppressor gene in epithelial cells and has been found to be mutated in 33 percent of colorectal tumors and cell lines studied. Rest could eventually serve as a marker for diagnosing colorectal and other types of cancer.
Bioinformatics
| Uniprot |
Human
Human
|
| Product By Gene ID |
5978 |
| Alternate Names |
- Neural-restrictive silencer factor
- NRSFneuron restrictive silencer factor
- RE1-silencing transcription factor
- X2 box repressor
- XBRrepressor binding to the X2 box
|
