Species: All-Multi
Applications: WB, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Description
Myosin heavy chain is a muscle myosin, which is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac myosin heavy chain exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the myosin heavy chain genes are associated with several different dilated and hypertrophic cardiomyopathies.
Bioinformatics
Uniprot |
Human |
Product By Gene ID |
79784 |
Alternate Names |
- DFNA4
- FLJ13881
- FLJ43092
- KIAA2034DKFZp667A1311
- MHC16
- MYH14 variant protein
- MYH17
- Myosin heavy chain 14
- Myosin heavy chain, non-muscle IIc
- myosin
- myosin, heavy chain 14
- myosin, heavy chain 14, non-muscle
- myosin, heavy polypeptide 14
- myosin-14
- NMHC II-C
- NMHC-II-C
- Non-muscle myosin heavy chain IIc
- nonmuscle myosin heavy chain II-C
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