Species: Hu, Ca, Dr
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
3993 |
| Alternate Names |
- HGLlethal giant larvae (Drosophila) homolog 2
- human giant larvae homolog
- lethal giant larvae homolog 2 (Drosophila)
- lethal(2) giant larvae protein homolog 2
- LGL2
|
