Species: Hu, Ca, Pm
Applications: WB, ICC/IF, IHC
Host: Mouse monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM 3 is the major ligand for LFA-1 in the resting state.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
3385 |
Alternate Names |
- CD50 antigen
- CD50
- CDW50CDw50
- ICAM-3
- ICAM-Rintercellular adhesion molecule-3
- intercellular adhesion molecule 3
|
Research Areas for ICAM-3/CD50
Find related products by research area and learn more about each of the different research areas below.
Cellular MarkersImmunology