CD99 Products

Description

CD99 is encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	4267 Human
Uniprot	AAH03147 Human NP_002405 Human NP_002405.1 Human P14209 Human
Product By Gene ID	4267
Alternate Names	12E7 CD99 antigenY homolog CD99 molecule E2 antigen HBA71 MIC2 (monoclonal 12E7) MIC2Y MSK5X Protein MIC2 surface antigen MIC2 T-cell surface glycoprotein E2

Research Areas for CD99

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Immunology