Calpain S1 Products

Description

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Bioinformatics

Entrez	826 Human
Uniprot	AAH00592 Human AAH07779 Human AAH07779.1 Human AAH21933.1 Human NP_001003962 Human NP_001740 Human P04632 Human
Product By Gene ID	826
Alternate Names	Calcium-activated neutral proteinase small subunit Calcium-dependent protease small subunit 1 calcium-dependent protease, small subunit calpain 4, small subunit (30K) Calpain regulatory subunit calpain small subunit 1 calpain, small polypeptide CALPAIN4 CANP CANPS CAPN4 CDPS CSS1 epididymis secretory sperm binding protein

Research Areas for Calpain S1

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Cell Cycle and Replication