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IL-12

Immune Cell Metabolic Flux Influences Type I Diabetes

Banner image showing mitochondrion and metabolic pathways and targets, from Tocris.

By Hunter Martinez

Tags: 
Adaptive Immunity
Diabetes
Type I Diabetes
Immunometabolism
Innate Immunity
Macrophage
metabolism
Mitochondria
mTOR Pathway
T Cells
ACSL1
CD4
COX-2
IL-1 beta/IL-1F2
IL-12
IL-18/IL-1F4
Insulin
MHC class II
PGE2
TNF-alpha
Hunter Martinez

Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity

IL10 receptor alpha expression in human colon carcinoma, IHC

By Jamshed Arslan, Pharm. D., PhD.

Tags: 
Cancer
Colorectal Cancer
Colon Cancer
Immunotherapy
immunology
T helper
Cytotoxic T cells
IL-10
IL-12
IFN-gamma
IL-10 R alpha
CD4
CD8
IL-17
Th17
ROR gamma t
Jamshed Arslan

You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers

TGF-beta signaling pathway

By Jamshed Arslan Pharm.D.

Tags: 
Natural Killer cells (NK)
Lymphocytes
Innate Immunity
immunology
Cancer
Cytokines
TGF-beta
cd16
NKG2D
IL-12
TNF-alpha
IFN-gamma
Perforin
granzyme
CD45

Ly6G Antibody - A Marker for Monocytes, Granulocytes and Neutrophils

What is Ly6G?

Tags: 
acute myeloid leukemia
IL-12
IL-17
IL-27
Ly-6G
Ly-6G antibodies
Ly-6G antibody
Ly6G antibody
MIP-2
secreted protein acidic and rich in cysteine