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Cancer

Unlocking the Potential of Biosimilars in Immuno-Oncology

By Jennifer Jones, M.S.

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NPC1: A Potential Target For Triple-Negative Breast Cancer

By Natalia Gurule, PhD

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Triple-Negative Breast Cancer

Niemann-Pick C1

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Hypoxia-Dependent CAR Stabilizing Construct in T cells Improves Solid Tumor Targeting and Efficacy

By Victoria Osinski, PhD

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Chimeric Antigen Receptor

Tumor Microenvironment

Victoria Osinski

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Synthetic Biotic Medicine as Immunotherapy Against Cancer: Evidence From Arginine-Producing Engineered Bacteria

By Jamshed Arslan, Pharm D, PhD

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Cancer Research

Checkpoint Blockade

Checkpoint Inhibitors

Immuno-oncology

Innate Immunity

Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy

By Victoria Osinski, PhD

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Understanding ‘Y’ in Breast Cancer: Crucial Role of DNA/RNA-binding Protein YB-1 in the Development, Pre-Invasive, and Metastatic Phases

Jamshed Arslan, Pharm D, PhD

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Carbonic Anhydrase IX/CA9

Taking Biomarker Discovery From 2D to 3D: Increased Biological Activity of EVs Isolated From 3D Prostate Cancer Cultures

Jamshed Arslan, Pharm D, PhD

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extracellular vesicles

Prostate Cancer

PSMA/FOLH1/NAALADase I

Matrix Metalloproteinase

Using CometChip to Characterize Extracellular Regulators of DNA Repair: Does CD73 Levels in Cancer Cells Affect DNA Repair by Regulating Levels of Intracellular NAD+?

By Natalia Gurule, PhD

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Base Excision Repair

Metabolic Signaling

Tumor Microenvironment

5’Nucleotidase/CD73

Nicotinamide Adenine Dinucleotide

Transcriptional co-activators Yap1 and Taz control growth and development

Schematic of Hippo signaling pathway highlighting Yap and Taz proteins.

By Jamshed Arslan, Pharm D, PhD

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Pattern recognition receptors (PRR) expression and function in endothelial cells

Banner image cartoon depicting a portion of the TLR signaling pathway.

By Victoria Osinski

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