MCP1 antibody

The Monocyte chemoattractant protein-1 (MCP1) is a member of the C-C chemokine family, and a potent chemotactic factor for monocytes.

MCP1, also known as CCL2, is a small chemokine factor belonging to the CC chemokine family. It is predominantly produced by endothelial cells and macrophages, and specifically is a chemoattractant for monocytes and basophils. It is produced by a wide range of cell types in reaction to diverse inflammatory stimuli including tissue injury, infection, and inflammation.

Monocyte Chemotactic Protein-1 (MCP-1), also known as Chemokine C-C motif Ligand 2 (CCL2), is a small cytokine involved in immune response, inflammation and tissue repair. Specifically, MCP1 is responsible for recruiting monocytes, memory T cells, and dendritic cells to sites of tissue injury or infection. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli, and has been implicated in many diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis.

LXR Alpha, also known as Liver X receptor Alpha is a 50KDa protein that belongs to the nuclear hormone receptor family located in the nucleus. It is specifically expressed in the liver, kidney and intestine; however it has also been found in the spleen, macrophages and the adrenals. All of these tissues play an important role in lipid metabolism. The primary role of LXR Alpha is to maintain cholesterol homeostasis in macrophages by regulating the genes involved in this.

We at Novus Biologicals recently added two new MCP1 antibodies to our antibody catalog. MCP1, also known as MCAF (monocyte chemotactic and activating factor) is released by a diverse range of cell types as part of the inflammatory response. A member of the SIG (small inducible gene) family, it is selective for monocytes and basophils, mainly to recruit monocytes to injury and infection sites.