MST2/STK3 Antibody (OTI4G10) Summary
Immunogen |
Full-length protein expressed in 293T cell transfected with human STK3 expression vector |
Specificity |
This antibody is specific for Homo sapiens serine/threonine kinase 3 (STE20 homolog, yeast) (STK3). |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
STK3 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:50
- Immunohistochemistry-Paraffin 1:50
- Western Blot 1:2000
|
Theoretical MW |
56.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH 7.3), 1.0% BSA and 50% Glycerol |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for MST2/STK3 Antibody (OTI4G10)
Background
Protein kinase activation is a frequent response of cells to treatment with growth factors,chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast ' sterile 20'(Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
FAQs for MST2/STK3 Antibody (NBP1-48017). (Showing 1 - 1 of 1 FAQ).
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Do you have any information on how this antibody was generated? ..show answer..
- The immunogen used to generate this antibody is the full-length protein. Unfortunately, we have not epitope mapped this clone; however, given that it is a licensed clone, there may be some publication information available with further details of the epitope.
Secondary Antibodies
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Isotype Controls
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