E-Cadherin Products

Description

E-cadherin, or epithelial cadherin, is an cell-cell adhesion glycoprotein important to cellular processes such as morphology, polarity, development, tissue integrity and migration. E cadherin's extracellular domain interacts with other E-cadherin protein on adjacent epithelial cells to establish adhesion between them. E cadherin has also been identified as a tumor and metastasis suppressor, and its mutations have been linked to various forms of cancer.

Bioinformatics

Entrez	12550 Mouse 282637 Bovine 51343 Human 83502 Rat 999 Human
Uniprot	ENSP00000261769 Human NM_004360 Human NP_004351 Human NP_004351 Human P09803 Mouse P12830 Human P12830 Human Q9UM11 Human
Product By Gene ID	999
Alternate Names	Arc-1 cadherin 1, E-cadherin (epithelial) cadherin 1, type 1, E-cadherin (epithelial) cadherin-1 calcium-dependent adhesion protein, epithelial CAM 120/80 CD324 antigen CD324 CDHE cell-CAM 120/80 ECAD E-cadherin Epithelial cadherin LCAM UVOE-Cadherin uvomorulin Uvomorulin

Research Areas for E-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Phospho-Specific
Plasma Membrane Markers
Signal Transduction

Related E-Cadherin Blog Posts

Check out the latest blog posts on E-Cadherin.

E-Cadherin in Cell-Cell Adhesion and Cancer Diagnostics E-Cadherin is a member of the cadherin superfamily and is fundamental player in a wide range of cellular processes such as development, morphology, polarity, migration and tissue integrity. Specifically, E-cadherin is an approximately 100 kDa epitheli...    Read more.

E-Cadherin as a Cancer Biomarker E-cadherin is a calcium-regulated adhesion molecule expressed in most normal epithelial tissues. E-cadherin is also associated with gland formation, stratification, and epithelial polarization, while loss of E-cadherin can cause dedifferentiation and ...    Read more.

Carbonic Anhydrase IX Roles in Tumor Growth, Survival and Invasion Carbonic anhydrase IX (CAIX) is a membrane-associated carbonic anhydrase, strongly induced by hypoxia. CA IX is overexpressed by several cancer cells from many tumor types, and is a component of the pH regulatory system invoked by these cells to comba...    Read more.

Vimentin: Regulating EMT and Cancer Vimentin, a member of the intermediate filament (IF) family, is a protein responsible for maintaining cellular integrity and reducing damage caused by stress. The vimentin protein is ubiquitously expressed in normal mesenchymal cells, and recent resea...    Read more.

SOX2 - a stem cell transcription factor The SOX gene family encodes a group of highly conserved transcription factors defined by the presence of a conserved high motility group (HMG) DNA-binding domain. They are involved in embryonic development regulation and cell fate determination. Al...    Read more.

Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...    Read more.

Beta-catenin - I am versatile! Beta-catenin is a cytosolic, 88 kDa intracellular protein associated with cell surface cadherin glycoproteins. It is a member of the larger calcium-dependent catenin family that includes alpha-catenin, beta-catenin, and gamma-catenin (also known as pl...    Read more.

Cathepsin B - a lysosomal protease with potential of an important drug target in neurological diseases and cancer Cathepsins are a family of lysosomal proteases (serine, aspartic and cysteine proteases) that acts in conjunction with lipases and nucleases to degrade biological macromolecules in the lysosomes (1). While most cathepsins are ubiquitously expressed...    Read more.

Read more E-Cadherin related blogs.