TGF-beta RIII Products

Description

Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1 (MIM 190180), TGFB2 (MIM 190220), and TGFB3 (MIM 190230). The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1; MIM 190181), type II (TFGBR2; MIM 190182), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form (Johnson et al., 1995 [PubMed 8530052]).

Bioinformatics

Entrez	7049 Human
Uniprot	AAA67061 Human NM_003243 Human NP_003234 Human NP_003234.2 Human Q03167 Human
Product By Gene ID	7049
Alternate Names	betaglycan proteoglycan betaglycan Betaglycan BGCAN TGF-beta receptor type 3 TGF-beta receptor type III TGFR-3 Transforming growth factor beta receptor III transforming growth factor beta receptor type 3 transforming growth factor, beta receptor III (betaglycan, 300kDa) transforming growth factor, beta receptor III

Research Areas for TGF-beta RIII

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Angiogenesis

Related TGF-beta RIII Blog Posts

Check out the latest blog posts on TGF-beta RIII.

TGF-beta RIII - A multi-functional regulator of the TGF-beta signaling pathway Transforming growth factor-beta receptor III (TGF-beta RIII) is one of three receptors for the secreted growth factor TGF-beta. Unlike type I and type II TGF-beta receptors, TGF-beta RIII does not participate directly in the propagation of intracel...    Read more.

TGF-beta RIII - a high affinity reservoir for TGF-beta I/II ligands with therapeutic potential TGF beta (transforming growth factor beta) is a superfamily of cytokines that participate in a variety of cellular processes including growth, proliferation, differentiation, and apoptosis. There are 3 classes of receptors for TGF beta cytokines an...    Read more.

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