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Zeta Opioid Receptor Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

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Zeta Opioid Receptor Antibody [Janelia Fluor® 669] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human Zeta Opioid Receptor fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OGFR
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Zeta Opioid Receptor Antibody [Janelia Fluor® 669]

  • 7-60 protein
  • 7-60
  • OGFr
  • opioid growth factor receptor
  • Protein 7-60
  • Zeta-type opioid receptor

Background

Zeta Opioid Receptor is the receptor for opioid growth factor (OGF), also known as Met-enkephalin. Met-enkephalin (met-Enk) is an opioid peptide that acts via three main subtypes of receptors referred to as mu, delta and zeta receptors. The first two receptor subtypes mediate the classic opioid effects of met-Enk, wheras zeta-receptors are reported to be involved in the non-opioid actions of the peptide. OGF (Met-enkephalin)is an inhibitory peptide that modulates cell proliferation and tissue organization during development, cellular renewal, cancer, wound healing, and angiogenesis. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. It has been found that the progression of some tumours is associated with the down regulation of opioid growth factor receptor expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol OGFR