Novus Biologicals products are now on bio-techne.com

USP7 Antibody (03) [DyLight 350]

Images

 
There are currently no images for USP7 Antibody (NBP3-06427UV).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, ELISA
Clone
03
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

Shipping $45.00 per order
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Datasheet
Reviews & Publications
Protocols & FAQs
Support & Research

USP7 Antibody (03) [DyLight 350] Summary

Immunogen
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human USP7 (Accession#: NP_003461.2; Lys208-Glu560).
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
USP7
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Sandwich ELISA Detection
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for USP7 Antibody (03) [DyLight 350]

  • Deubiquitinating enzyme 7
  • EC 3.1.2.15
  • EC 3.4.19.12
  • HAUSP
  • HAUSPTEF1
  • Herpes virus-associated ubiquitin-specific protease
  • Herpesvirus-associated ubiquitin-specific protease
  • TEF1
  • ubiquitin carboxyl-terminal hydrolase 7
  • ubiquitin specific peptidase 7 (herpes virus-associated)
  • ubiquitin specific protease 7 (herpes virus-associated)
  • Ubiquitin thioesterase 7
  • Ubiquitin-specific-processing protease 7
  • USP7

Background

HAUSP (also known as deubiquitinating enzyme 7, herpes virus associated ubiquitin specific protease, TEF1, ubiquitin carboxyl terminal hydrolase 7, ubiquitin specific protease 7, ubiquitin thiolesterase 7, and USP7) is a novel p53 interacting protein. HAUSP was identified by mass spectrometry of affinity-purified p53 associated factors by Li et al. HAUSP strongly stabilizes p53 even in the presence of excess MDM2, and also induces p53-dependent cell growth repression and apoptosis. HAUSP has an intrinsic enzymatic activity that specifically de-ubiquitinates p53 both in vivo and in vitro. Expression of a catalytically inactive point mutation of HAUSP in cells increased the levels of p53 ubiquitination and also destabilized p53. Li et al concluded that their findings revealed an important mechanism by which p53 can be stabilized by direct de-ubiquitination and also implied that HAUSP may function as a tumor suppressor in vivo through the stabilization of p53.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-86037
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NB200-103
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information


Product PDFs

  SDS

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our USP7 Antibody (03) [DyLight 350] and receive a gift card or discount.

Bioinformatics

Gene Symbol USP7