UBR5/EDD Antibody

This is a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22, a locus disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NB100-1220	Applications	Species
Garbow JR, Doherty JM, Schugar RC et al. Hepatic steatosis, inflammation, and ER stress in mice maintained long-term on a very low-carbohydrate ketogenic diet. Am J Physiol Gastrointest Liver Physiol;300(6):G956-67. 2011-06-01 [PMID: 21454445]
Henderson MJ, Russell AJ, Hird S et al. EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response. J Biol Chem 2002-07-19 [PMID: 12011095]

Array NB100-1220

• UBR5/EDD Antibodies
• UBR5/EDD Protein