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Tie-2 Antibody (B-B48) - Azide and BSA Free

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Flow Cytometry: Tie-2 Antibody (B-B48) [NBP3-14575] - A typical staining pattern with the B-B48 monoclonal antibody of Eahy 926 cell line.
Flow Cytometry: Tie-2 Antibody (B-B48) [NBP3-14575] - A typical staining pattern with the B-B48 monoclonal antibody of Eahy 926 cell line.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func
Clone
B-B48
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-14575AF350
Alexa Fluor 405
NBP3-14575AF405
Alexa Fluor 488
NBP3-14575AF488
Alexa Fluor 532
NBP3-14575AF532
Alexa Fluor 594
NBP3-14575AF594
Alexa Fluor 647
NBP3-14575AF647
Alexa Fluor 700
NBP3-14575AF700
Alexa Fluor 750
NBP3-14575AF750
Allophycocyanin
NBP3-14575APC
Biotin
NBP3-14575B
DyLight 350
NBP3-14575UV
DyLight 405
NBP3-14575V
DyLight 488
NBP3-14575G
DyLight 550
NBP3-14575R
DyLight 594
NBP3-14575DL594
DyLight 650
NBP3-14575C
DyLight 680
NBP3-14575FR
DyLight 755
NBP3-14575IR
FITC
NBP3-14575F
HRP
NBP3-14575H
Janelia Fluor 549
NBP3-14575JF549
Janelia Fluor 646
NBP3-14575JF646
PE
NBP3-14575PE
PerCP
NBP3-14575PCP
mFluor Violet 450 SE
NBP3-14575MFV450
mFluor Violet 500 SE
NBP3-14575MFV500
mFluor Violet 610 SE
NBP3-14575MFV610
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP3-14575-500ul
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Tie-2 Antibody (B-B48) - Azide and BSA Free Summary

Description
Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
Immunogen
Eahy 926 cell line
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TEK
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Functional
Application Notes
Biological Activity: Inhibits Tek-L / Tek binding

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS. Sterile-filtered through 0.22 um.
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Affinity purified

Alternate Names for Tie-2 Antibody (B-B48) - Azide and BSA Free

  • angiopoietin-1 receptor
  • CD202b antigen
  • CD202b
  • EC 2.7.10
  • EC 2.7.10.1
  • hTIE2
  • p140 TEK
  • soluble TIE2 variant 1
  • soluble TIE2 variant 2
  • TEK tyrosine kinase, endothelial
  • TEK
  • Tie2
  • Tie-2
  • TIE2CD202b
  • Tunica interna endothelial cell kinase
  • Tyrosine-protein kinase receptor TEK
  • Tyrosine-protein kinase receptor TIE-2
  • venous malformations, multiple cutaneous and mucosal
  • VMCM
  • VMCM1

Background

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Tie-2 Antibody (NBP3-14575) (0)

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Product General Protocols

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FAQs for Tie-2 Antibody (NBP3-14575) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TEK