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Solute carrier family 22 member 18 Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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Solute carrier family 22 member 18 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human Solute carrier family 22 member 18.

Source: E. coli

Amino Acid Sequence: TQGLVIGQLSSHFSEEVLLR

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
SLC22A18
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-56316.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for Solute carrier family 22 member 18 Recombinant Protein Antigen

  • BWR1AORCTL2
  • BWSCR1Asolute carrier family 22 (organic cation transporter), member 1-like
  • Efflux transporter-like protein
  • HET
  • imprinted multi-membrane spanning polyspecific transporter-related protein 1
  • Imprinted multi-membrane-spanning polyspecific transporter-related protein 1
  • IMPT1DKFZp667A184
  • ITMp45-BWR1A
  • ORCTL-2
  • organic cation transporter-like 2
  • Organic cation transporter-like protein 2
  • p45 Beckwith-Wiedemann region 1A
  • SLC22A1Lcandidate A
  • solute carrier family 22 member 18
  • Solute carrier family 22 member 1-like
  • solute carrier family 22, member 18
  • TSSC5p45-Beckwith-Wiedemann region 1 A
  • Tumor-suppressing STF cDNA 5 protein
  • Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein

Background

Solute carrier family 22 member 18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Solute carrier family 22 member 18 Recombinant Protein Antigen
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Bioinformatics

Gene Symbol SLC22A18