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RNF139 Antibody (3D10)

Images

 
Western Blot: RNF139 Antibody (3D10) [H00011236-M01] - RNF139 monoclonal antibody (M01), clone 3D10 Analysis of RNF139 expression in HepG2.
Immunohistochemistry-Paraffin: RNF139 Antibody (3D10) [H00011236-M01] - Analysis of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. Antibody concentration 3 ug/ml.
Sandwich ELISA: RNF139 Antibody (3D10) [H00011236-M01] - Detection limit for recombinant GST tagged RNF139 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
3D10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

RNF139 Antibody (3D10) Summary

Immunogen
RNF139 (NP_009149, 565 a.a. ~ 664 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFNDDTD
Specificity
RNF139 - ring finger protein 139
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RNF139
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Publications
Read Publication using H00011236-M01.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RNF139 Antibody (3D10)

  • EC 6.3.2.-
  • HRCA1
  • patched related protein translocated in renal cancer
  • RCA1multiple membrane spanning receptor TRC8
  • ring finger protein 139MGC31961
  • Translocation in renal carcinoma on chromosome 8 protein
  • TRC8E3 ubiquitin-protein ligase RNF139

Background

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for RNF139 Antibody (H00011236-M01)(1)


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RNF139
Entrez
OMIM
Uniprot