Quantikine Immunoassay Control Set 905 for Human NT-ProANP Summary
| Additional Information |
For use with catalog number DANP00 |
| Details of Functionality |
None<br /><br /> |
| Source |
N/A |
| Inter-Assay |
See PDF Datasheet for details |
| Intra-Assay |
See PDF Datasheet for details |
| Spike Recovery |
See PDF Datasheet for details |
| Sample Volume |
See PDF Datasheet for details |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Set 905 for Human NT-ProANP
Background
Atrial Natriuretic peptide (ANP) is synthesized as a 151 aa preproprotein. The proprotein contains cardiodilatin (aa 26 - 92) and atrial natriuretic factor (ANF; aa 124 - 151) which become active after processing by the serine protease corin. ANP is primarily synthesized in the heart and is secreted in response to atrial distention. ANF circulates in the plasma, eliciting natriuretic, diuretic, vasorelaxant and antimitogenic effects directed toward reduction of body fluid and blood pressure regulation. ANF acts through the cGMP-coupled NP receptor A. Human ANP and ANF share 84% and 96% aa identity with mouse ANP and ANF, respectively.
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