PIP Antibody (PIP/9076R) [Janelia Fluor® 635] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant fragment (around aa 1-146) of human PIP protein (exact sequence is proprietary) |
Localization |
Cytoplasm (Golgi bodies). Secreted. |
Marker |
Breast Marker |
Specificity |
It recognizes a protein of 15kDa, identified as Gross cystic disease fluid protein 15 (GCDFP-15). This antibody is useful in the identification of metastatic breast carcinoma, or fluid analysis. |
Isotype |
IgG Kappa |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
PIP |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Paraffin
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for PIP Antibody (PIP/9076R) [Janelia Fluor® 635]
Background
The androgen and prolactin responsive prolactin-inducible protein (PIP), also known as Gross cystic disease fluid protein (GCDFP-15) is expressed in benign and malignant human breast tumors and in such normal exocrine organs as sweat, salivary and lacrimal glands. The hormonally responsive PIP gene is expressed in benign and malignant breast tumor tissues and in such normal exocrine organs as sweat, salivary, and lacrimal glands. The cells within the body that produce PIP/GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found PIP to be a highly specific and sensitive marker for breast cancer.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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