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Phospho-Tyrosine Antibody (PY2870R) [DyLight 350]

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Product Details

Summary
Reactivity All-NASpecies Glossary
Applications ELISA
Clone
PY2870R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

Phospho-Tyrosine Antibody (PY2870R) [DyLight 350] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant full-length human Phospho-Tyrosine protein
Localization
Depends upon the location of phosphorylated target
Specificity
Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. Antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine containing proteins. This monoclonal antibody shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin/paraffin tissues.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Phospho-Tyrosine Antibody (PY2870R) [DyLight 350]

  • 2 amino 3(4 hydroxyphenyl) propanoic acid
  • 4 hydroxyphenylalanine
  • PhosphoTyrosine
  • pTyrosine
  • pY20
  • Tyrosine

Background

Phosphotyrosine is the phosphorylated version of the amino acid tyrosine. Phosphorylation of histidine, serine, threonine and tyrosine residues acts as a signalling system to control many cellular signalling pathways. The cellular networks which rely on these signals can be very complex, so phosphorylation often occurs on multiple sites on a given protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional Phospho-Tyrosine Products

Array NBP3-08423UV

Research Areas for Phospho-Tyrosine Antibody (NBP3-08423UV)

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Blogs on Phospho-Tyrosine

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