![Immunocytochemistry/Immunofluorescence: Perforin Antibody (deltaG9) [NBP1-45774] - Isolated CD8 T-cells showing intracellular perforin (green).](http://images.novusbio.com/fullsize/Perforin-Antibody-deltaG9-Immunocytochemistry-Immunofluorescence-NBP1-45774-img0001.jpg "Immunocytochemistry/Immunofluorescence: Perforin Antibody (deltaG9) [NBP1-45774] - Isolated CD8 T-cells showing intracellular perforin (green).")
| Immunogen | Purified granules from human YT lymphoma cells. |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | PRF1 |
| Purity | Affinity purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
|
|
| Publications |
|
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Buffer | 50 mM Sodium phosphate (pH 7.5), 100 mM Potassium chloride, 150 mM NaCl |
| Preservative | 0.5 mg/mL gentamicin sulfate |
| Concentration | 1.0 mg/ml |
| Purity | Affinity purified |
| Publication using NBP1-45774 | Applications | Species |
|---|---|---|
| Drvar V, Curko Cofek B, Karleusa L Granulysin expression and granulysin mediated apoptosis in the peripheral blood of osteoarthritis patients BioBIOMEDICAL REPORTS 2022-01-01 [PMID: 35478928] (cells, Human) | cells | Human |
Secondary Antibodies |
Isotype Controls |
Research Areas for Perforin Antibody (NBP1-45774)Find related products by research area.
|
|
You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers By Jamshed Arslan Pharm.D. Natural killer (NK) cells are lymphocytes of the innate immune system that were first discovered for their “natural” ability to kill cancer cells. To use NK cells as anti-cancer therapy, t... Read full blog post. |
|
Perforin a Protective Serial Killer Secretory granule-mediated cell death is one of the the key mechanisms for elimination of virus-infected and transformed target cells by cytotoxic lymphocytes. Formation of the immunological synapse between an effector and a target cell leads to exocy... Read full blog post. |
|
Perforin Antibodies Reveal Links to Apoptosis and Immune Response Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel... Read full blog post. |
|
Perforin Antibodies for Detecting Immune System Diseases Perforin is a calcium-dependent pore forming cytolytic protein. Perforin is partially homologous to the terminal components of the membrane attack complex of complement and produces pores of up to 20nm in diameter on target membranes. Killer lymphocy... Read full blog post. |
|
Perforin Antibodies Reveal Links to Apoptosis and Immune Response Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel... Read full blog post. |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
