| Reactivity | Hu, MuSpecies Glossary |
| Applications | WB, IP |
| Clone | CE2.10 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Janelia Fluor 635 |
| Immunogen | Recombinant mouse perforin (aa 98-534). |
| Specificity | Recognizes an epitope in the region aa 402-534 of human and mouse perforin. Does NOT detect Human in Western Blot. |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | PRF1 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
![Perforin Antibody (CE2.10) [Janelia Fluor® 635]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "Perforin Antibody (CE2.10) [Janelia Fluor® 635]")
Secondary Antibodies |
Isotype Controls |
Research Areas for Perforin Antibody (NBP1-97440JF635)Find related products by research area.
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Perforin a Protective Serial Killer Secretory granule-mediated cell death is one of the the key mechanisms for elimination of virus-infected and transformed target cells by cytotoxic lymphocytes. Formation of the immunological synapse between an effector and a target cell leads to exocy... Read full blog post. |
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Perforin Antibodies Reveal Links to Apoptosis and Immune Response Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel... Read full blog post. |
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Perforin Antibodies for Detecting Immune System Diseases Perforin is a calcium-dependent pore forming cytolytic protein. Perforin is partially homologous to the terminal components of the membrane attack complex of complement and produces pores of up to 20nm in diameter on target membranes. Killer lymphocy... Read full blog post. |
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Perforin Antibodies Reveal Links to Apoptosis and Immune Response Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel... Read full blog post. |
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| Gene Symbol | PRF1 |
