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Recombinant Human PEA-15 Protein

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SDS-Page: PEA15 Protein [NBP1-30247] - PEA-15, 15 kDa (130aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human PEA-15 Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids 1-130 of Human PEA-15

Source: E.coli

Amino Acid Sequence: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PEA15
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 7.5), 1 mM DTT, 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human PEA-15 Protein

  • HMAT1
  • HMAT115kD
  • HUMMAT1H
  • MAT1H
  • PEA15
  • PEA-15
  • PED
  • PED15 kDa phosphoprotein enriched in astrocytes
  • phosphoprotein enriched in astrocytes 15
  • Phosphoprotein enriched in diabetes

Background

Phospho-enriched protein in astrocytes 15 kDa (PEA-15) is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. Recombinant human PEA-15 was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for PEA-15 Protein (NBP1-30247) (0)

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Bioinformatics

Gene Symbol PEA15