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Numb Antibody Blocking Peptide

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications AC
Concentration
1.0 mg/ml

Order Details

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Numb Antibody Blocking Peptide Summary

Description
A NUMB antibody blocking peptide.
Specificity
This peptide is specific for NB500-178 only.
Protein/Peptide Type
Antibody Blocking Peptide
Gene
NUMB

Applications/Dilutions

Dilutions
  • Antibody Competition
Application Notes
This peptide is useful as a blocking peptide for NB500-178. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Peptide dissolved in dH2O. Contains no BSA.
Preservative
No Preservative
Concentration
1.0 mg/ml

Alternate Names for Numb Antibody Blocking Peptide

  • h-Numb
  • mnb
  • m-numb
  • numb (Drosophila) homolog
  • numb homolog (Drosophila)
  • Numb
  • protein numb homolog
  • Protein S171
  • S171

Background

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for Numb Peptide (NB500-178PEP) (0)

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Bioinformatics

Gene Symbol NUMB