Home » Numb » Numb Antibodies » Numb Antibody (OTI1B5) [Janelia Fluor® 585]
Novus Biologicals products are now on bio-techne.com

Numb Antibody (OTI1B5) [Janelia Fluor® 585]

 Submit a Review

Images

 
There are currently no images for Numb Antibody (NBP2-73130JF585).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI1B5
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73130AF350
Alexa Fluor 405
NBP2-73130AF405
Alexa Fluor 488
NBP2-73130AF488
Alexa Fluor 532
NBP2-73130AF532
Alexa Fluor 594
NBP2-73130AF594
Alexa Fluor 647
NBP2-73130AF647
Alexa Fluor 700
NBP2-73130AF700
Alexa Fluor 750
NBP2-73130AF750
Allophycocyanin
NBP2-73130APC
Biotin
NBP2-73130B
CoraFluor 1
NBP2-73130CL1
DyLight 350
NBP2-73130UV
DyLight 405
NBP2-73130V
DyLight 488
NBP2-73130G
DyLight 550
NBP2-73130R
DyLight 594
NBP2-73130DL594
DyLight 650
NBP2-73130C
DyLight 680
NBP2-73130FR
DyLight 755
NBP2-73130IR
FITC
NBP2-73130F
HRP
NBP2-73130H
Janelia Fluor 525
NBP2-73130JF525
Janelia Fluor 549
NBP2-73130JF549
Janelia Fluor 635
NBP2-73130JF635
Janelia Fluor 646
NBP2-73130JF646
Janelia Fluor 669
NBP2-73130JF669
PE
NBP2-73130PE
PerCP
NBP2-73130PCP
Unconjugated
NBP2-46284
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46284
Azide and BSA Free
NBP2-73130
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Numb Antibody (OTI1B5) [Janelia Fluor® 585] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-365 of human NUMB (NP_001005744) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NUMB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Numb Antibody (OTI1B5) [Janelia Fluor® 585]

  • h-Numb
  • mnb
  • m-numb
  • numb (Drosophila) homolog
  • numb homolog (Drosophila)
  • Numb
  • protein numb homolog
  • Protein S171
  • S171

Background

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NUMBL Antibody
NB100-88136
Immunoprecipitation NUMBL Antibody
Species: Hu
Applications: IP, WB (-)
Notch-1 Antibody
(mN1A) - BSA Free
NB100-78486
Immunohistochemistry-Paraffin Notch-1 Antibody (mN1A) - BSA Free
Knockout Validated Notch-1 Antibody (mN1A) - BSA Free
Flow Cytometry Notch-1 Antibody (mN1A) - BSA Free
(2 Reviews)
(10 Publications)
Species: Hu, Mu, Rt(-)
Applications: CyTOF-ready, Flow, ICC/IF, IHC, IHC-P, IP, KO, WB
Lnx1 Antibody
NBP1-80518
Western Blot Lnx1 Antibody
Western Blot Lnx1 Antibody
Species: Hu
Applications: WB
PARD3/Par3 Antibody
NBP1-88861
Immunohistochemistry-Paraffin PARD3/Par3 Antibody
Immunohistochemistry-Paraffin PARD3/Par3 Antibody
Immunohistochemistry-Paraffin PARD3/Par3 Antibody
(2 Reviews)
(10 Publications)
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, IP, Simple Western, WB
INSC Antibody
NBP1-90980
Immunohistochemistry INSC Antibody
Species: Hu
Applications: IHC, IHC-P
ZNF645 Antibody
NBP2-21037
Western Blot ZNF645 Antibody
Immunohistochemistry-Paraffin ZNF645 Antibody
Species: Hu
Applications: IHC, IHC-P, WB
MUL1 Antibody
(5H6.2D5) - BSA Free
NBP2-31361
Western Blot MUL1 Antibody (5H6.2D5) - BSA Free
Immunohistochemistry-Paraffin MUL1 Antibody (5H6.2D5) - BSA Free
Immunohistochemistry-Paraffin MUL1 Antibody (5H6.2D5) - BSA Free
Species: Hu
Applications: IHC, IHC-P, WB
TRIM50 Antibody
NBP1-81988
Immunohistochemistry-Paraffin TRIM50 Antibody
Species: Hu
Applications: IHC, IHC-P
PTBP2 Antibody
NBP2-19997
Western Blot PTBP2 Antibody
Immunohistochemistry-Paraffin PTBP2 Antibody
Western Blot PTBP2 Antibody
(1 Publication)
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
PTBP1 Antibody
(3H8)
H00005725-M01
Western Blot PTBP1 Antibody (3H8)
Western Blot PTBP1 Antibody (3H8)
Western Blot PTBP1 Antibody (3H8)
(4 Publications)
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, Single-Cell Western, WB
p53 Antibody (PAb
240) - BSA Free
NB200-103
Flow Cytometry p53 Antibody (PAb 240) - BSA Free
Flow Cytometry p53 Antibody (PAb 240) - BSA Free
Flow (Intracellular) p53 Antibody (PAb 240) - BSA Free
(3 Reviews)
(42 Publications)
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
beta Amyloid
Antibody (MOAB-2) - B ...
NBP2-13075
Immunohistochemistry-Frozen beta Amyloid Antibody (MOAB-2) - BSA Free
Immunohistochemistry beta Amyloid Antibody (MOAB-2) - BSA Free
Immunocytochemistry/ Immunofluorescence beta Amyloid Antibody (MOAB-2) - BSA Free
(2 Reviews)
(70 Publications)
Species: Ba, Hu, Pm, Mu, Rt
Applications: DB, ELISA, IB, ICC/IF, IHC-FrFl, IHC, IHC-Fr, IHC-P, IP, WB
GPSM2 Antibody
NBP1-53125
Immunohistochemistry GPSM2 Antibody
Western Blot GPSM2 Antibody
Immunocytochemistry/ Immunofluorescence GPSM2 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NM23-H1 Antibody
NBP1-80992
Immunohistochemistry-Paraffin NM23-H1 Antibody
Immunohistochemistry-Paraffin NM23-H1 Antibody
Immunohistochemistry-Paraffin NM23-H1 Antibody
(2 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
PXR/NR1I2 Antibody
(H4417) [Unconjugated ...
PP-H4417-00
PXR/NR1I2 Antibody (H4417) [Unconjugated]
(2 Publications)
Species: Hu
Applications: DirELISA, IP, WB
PAR3/Thrombin
Receptor-like 2 Antib
NLS261
Immunohistochemistry-Paraffin PAR3/Thrombin Receptor-like 2 Antibody
Immunohistochemistry-Paraffin PAR3/Thrombin Receptor-like 2 Antibody
Immunohistochemistry-Paraffin PAR3/Thrombin Receptor-like 2 Antibody
Species: Hu
Applications: ICC, IHC, IHC-P, WB (-)
DAN/NBL1 Antibody
[Unconjugated]
AF755
DAN/NBL1 Antibody [Unconjugated]
(1 Publication)
Species: Mu
Applications: Block, WB
Numb Antibody
(OTI1B5) [Janelia Flu ...
NBP2-73130JF585
Numb Antibody (OTI1B5) [Janelia Fluor® 585]
Species: Hu, Mu, Rt
Applications: WB, IHC

Publications for Numb Antibody (NBP2-73130JF585) (0)

There are no publications for Numb Antibody (NBP2-73130JF585).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Numb Antibody (NBP2-73130JF585) (0)

There are no reviews for Numb Antibody (NBP2-73130JF585). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Numb Antibody (NBP2-73130JF585) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Numb Products

Research Areas for Numb Antibody (NBP2-73130JF585)

Find related products by research area.

Blogs on Numb

There are no specific blogs for Numb, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Mouse brain (cerebral cortex). Red: MOAB-2 antibody staining, Blue: DAPI. Zeiss LSM800, 40x. Image from verified customer review.
beta Amyloid Antibody (MOAB-2) - BSA Free
NBP2-13075
Flow Cytometry: p53 Antibody (PAb 240) [NB200-103] - An intracellular stain was performed on HeLa cells with p53 (PAb240) NB200-103AF647 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647.
p53 Antibody (PAb 240) - BSA Free
NB200-103

Contact Information

Product PDFs

  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Numb Antibody (OTI1B5) [Janelia Fluor® 585] and receive a gift card or discount.


Bioinformatics

Gene Symbol NUMB