NMDA R, NR1 Subunit Antibody (R1JHL) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 3 of 3.

Publications using PPS011B	Applications	Species
Yan-Jiao Wu, Xin Yi, Xue Gu, Qi Wang, Qin Jiang, Ying Li et al. Synaptic scaling of corticostriatal circuits underlies hyperactivity in GABA Transporter-1 deficient mice iScience 2023-04-21 [PMID: 36968092]
Zhe Yu, Yan-Jiao Wu, Yi-Zhi Wang, Di-Shi Liu, Xing-Lei Song, Qin Jiang et al. The acid-sensing ion channel ASIC1a mediates striatal synapse remodeling and procedural motor learning Science Signaling 2018-08-09 [PMID: 30087178]
ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion Nat Commun, 2016-12-07;7(0):13770. 2016-12-07 [PMID: 27924869] (Western Blot, Mouse)	Western Blot	Mouse

Array PPS011B

• NMDA R, NR1 Subunit Antibodies