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Neuropilin-1 Antibody (vesencumab)

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Immobilized human NRP1 His at 2 ug/mL can bind Neuropilin-1 Antibody (vesencumab), EC50=0.005571 ug/mL.
Immobilized human NRP1 His at 2 ug/mL can bind Neuropilin-1 Antibody (vesencumab), EC50=0.005571 ug/mL.
Human NRP1 HEK293 cells were stained with Neuropilin-1 Antibody (vesencumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.1948 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
vesencumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28569AF350
Alexa Fluor 405
NBP3-28569AF405
Alexa Fluor 488
NBP3-28569AF488
Alexa Fluor 532
NBP3-28569AF532
Alexa Fluor 594
NBP3-28569AF594
Alexa Fluor 647
NBP3-28569AF647
Alexa Fluor 700
NBP3-28569AF700
Alexa Fluor 750
NBP3-28569AF750
Allophycocyanin
NBP3-28569APC
Biotin
NBP3-28569B
CoraFluor 1
NBP3-28569CL1
DyLight 350
NBP3-28569UV
DyLight 405
NBP3-28569V
DyLight 488
NBP3-28569G
DyLight 550
NBP3-28569R
DyLight 594
NBP3-28569DL594
DyLight 650
NBP3-28569C
DyLight 680
NBP3-28569FR
DyLight 755
NBP3-28569IR
FITC
NBP3-28569F
HRP
NBP3-28569H
Janelia Fluor 525
NBP3-28569JF525
Janelia Fluor 549
NBP3-28569JF549
Janelia Fluor 585
NBP3-28569JF585
Janelia Fluor 635
NBP3-28569JF635
Janelia Fluor 646
NBP3-28569JF646
Janelia Fluor 669
NBP3-28569JF669
PE
NBP3-28569PE
PerCP
NBP3-28569PCP
mFluor Violet 450 SE
NBP3-28569MFV450
mFluor Violet 500 SE
NBP3-28569MFV500
mFluor Violet 610 SE
NBP3-28569MFV610
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Neuropilin-1 Antibody (vesencumab) Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'vesencumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
NRP1 / VEGF165R / CD304
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
NRP1
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Neuropilin-1 Antibody (vesencumab)

  • BDCA4
  • BDCA-4
  • CD304 antigen
  • CD304
  • DKFZp686A03134
  • DKFZp781F1414
  • neuropilin 1
  • Neuropilin1
  • Neuropilin-1
  • NP1
  • NRP
  • NRP1
  • transmembrane receptor
  • Vascular endothelial cell growth factor 165 receptor
  • VEGF165R

Background

Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Immunohistochemistry VEGFR1/Flt-1 Antibody [Unconjugated]
Western Blot VEGFR1/Flt-1 Antibody [Unconjugated]
(2 Reviews)
(73 Publications)
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Immunohistochemistry-Paraffin NELL2 Antibody
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(2 Publications)
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Semaphorin 3A
[Unconjugated]
1250-S3
Bioactivity Semaphorin 3A [Unconjugated]
(34 Publications)
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Semaphorin 3F
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3237-S3
Semaphorin 3F [Unconjugated]
(8 Publications)
Species: Mu
Applications: BA
PLGF [HRP]
DPG00
N/A PLGF [HRP]
N/A PLGF [HRP]
N/A PLGF [HRP]
(79 Publications)
Species: Hu
Applications: ELISA
Plexin A1 Antibody
[Unconjugated]
AF4309
Immunohistochemistry Plexin A1 Antibody [Unconjugated]
Immunocytochemistry Plexin A1 Antibody [Unconjugated]
Western Blot Plexin A1 Antibody [Unconjugated]
(12 Publications)
Species: Hu, Mu
Applications: ICC, IHC, WB
Semaphorin 3B
Antibody
NB100-2218
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Immunocytochemistry/ Immunofluorescence Semaphorin 3B Antibody
(2 Publications)
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Neuronal Pentraxin
2 Antibody - BSA Free ...
NBP1-76899
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Species: Hu, Mu, Rt
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AF887
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(49 Publications)
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VEGFR3/Flt-4
Antibody [Unconjugate
AF743
Flow Cytometry VEGFR3/Flt-4 Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence VEGFR3/Flt-4 Antibody [Unconjugated]
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ERK1 Antibody
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NBP2-22203
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(1 Publication)
Species: Hu, Pm, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
Neuropilin-1
Antibody (vesencumab)
NBP3-28569
Neuropilin-1 Antibody (vesencumab)
Species: Hu
Applications: ELISA, Flow, Func

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FAQs for Neuropilin-1 Antibody (NBP3-28569). (Showing 1 - 2 of 2 FAQ).

  1. If this product is used in an application or species as a part of a customer review, will that validate this product in the application/species?
    • If any of our primary antibodes are used in an untested application or species and it is shown to work through images from customer reviews or through publications, this validates the application/species for this product. Please check out our Innovator's Reward Program if you decide to test an antibody with a species or application that is not currently listed.
  2. What research areas can Neuropilin-1 antibodies be used in?
    • Neuropilin-1 products can be applied in the following research areas: Adaptive Immunity, Angiogenesis, Breast Cancer, Cancer, Cardiovascular Biology, Neuroscience, and Virology Bacteria and Parasites.

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Bioinformatics

Gene Symbol NRP1
Uniprot