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Neuropilin-1 Antibody (446921) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
446921
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3870U-100UG
Alexa Fluor 405
FAB3870V-100UG
Alexa Fluor 488
FAB3870G-100UG
Alexa Fluor 532
FAB3870X
Alexa Fluor 594
FAB3870T-100UG
Alexa Fluor 647
FAB3870R-100UG
Alexa Fluor 700
FAB3870N-100UG
Alexa Fluor 750
FAB3870S-100UG
Allophycocyanin
FAB3870A-025
Allophycocyanin
FAB3870A-100
Allophycocyanin/Cy7
FAB3870APCCY7
Biotin
FAB3870B
CoraFluor 1
FAB3870CL1
DyLight 350
FAB3870D
DyLight 405
FAB3870E
DyLight 488
FAB3870K
DyLight 550
FAB3870L
DyLight 594
FAB3870M
DyLight 650
FAB3870W
DyLight 680
FAB3870Y
DyLight 755
FAB3870Z
Fluorescein
FAB3870F-100
HRP
FAB3870H
Janelia Fluor 549
FAB3870I
Janelia Fluor 585
FAB3870JF585
Janelia Fluor 635
FAB3870JF635
Janelia Fluor 646
FAB3870J
Janelia Fluor 669
FAB3870JF669
PE/Atto594
FAB3870PEATT594
PE/Cy5.5
FAB3870PECY55
PE/Cy7
FAB3870PECY7
Phycoerythrin
FAB3870P-025
Phycoerythrin
FAB3870P-100
Unconjugated
MAB3870
mFluor Violet 450 SE
FAB3870MFV450
mFluor Violet 500 SE
FAB3870MFV500
mFluor Violet 610 SE
FAB3870MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3870
Carrier Free
MAB3870
Carrier Free
MAB3870-SP
Carrier Free
FAB3870P-100
Carrier Free
FAB3870P-025
Carrier Free
FAB3870F-100
Carrier Free
FAB3870A-100
Carrier Free
FAB3870A-025
Carrier Free
FAB3870V-100UG
Carrier Free
FAB3870U-100UG
Carrier Free
FAB3870T-100UG
Carrier Free
FAB3870S-100UG
Carrier Free
FAB3870R-100UG
Carrier Free
FAB3870G-100UG
Carrier Free
FAB3870N-100UG
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Neuropilin-1 Antibody (446921) [Janelia Fluor® 525] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Neuropilin‑1
Phe22-Lys644
Accession # NP_001019799
Specificity
Detects human Neuropilin-1 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NRP1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Neuropilin-1 Antibody (446921) [Janelia Fluor® 525]

  • BDCA4
  • BDCA-4
  • CD304 antigen
  • CD304
  • DKFZp686A03134
  • DKFZp781F1414
  • neuropilin 1
  • Neuropilin1
  • Neuropilin-1
  • NP1
  • NRP
  • NRP1
  • transmembrane receptor
  • Vascular endothelial cell growth factor 165 receptor
  • VEGF165R

Background

Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Neuropilin-1
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FAB3870JF525
Neuropilin-1 Antibody (446921) [Janelia Fluor® 525]
Species: Hu
Applications: Flow, CyTOF-ready

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FAQs for Neuropilin-1 Antibody (FAB3870JF525). (Showing 1 - 2 of 2 FAQ).

  1. If this product is used in an application or species as a part of a customer review, will that validate this product in the application/species?
    • If any of our primary antibodes are used in an untested application or species and it is shown to work through images from customer reviews or through publications, this validates the application/species for this product. Please check out our Innovator's Reward Program if you decide to test an antibody with a species or application that is not currently listed.
  2. What research areas can Neuropilin-1 antibodies be used in?
    • Neuropilin-1 products can be applied in the following research areas: Adaptive Immunity, Angiogenesis, Breast Cancer, Cancer, Cardiovascular Biology, Neuroscience, and Virology Bacteria and Parasites.

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Bioinformatics

Gene Symbol NRP1